Inflammatory cytokines in newborn infants

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Inflammatory cytokines in newborn infants.

Serum levels of IL-1beta, IL-6 and TNF-alpha were measured in 48 healthy, termed neonates on the 1st (N1), 5th (N5) and 40th (N40) day after birth, compared with those in maternal serum (MS), umbilical cord (UC) and adult controls. Cytokine values in N1 and N5 were significantly elevated, than those in UC and in controls (P<0.0001). IL-1beta and IL-6 declined significantly from N1 to N40 (P<0.0...

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Age-related differentiations of Th1/Th2 cytokines in newborn infants.

OBJECTIVE To evaluate age-related differentiation of immune response in newborns by measuring serum concentrations of interleukin-2 (IL-2), interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) during the perinatal period. SUBJECTS AND METHODS Fifty-seven healthy term neonates, their mothers and 25 healthy adults (controls) age-matched to the mothers were included in the study. Cytokine conce...

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Thrombosis in newborn infants.

The incidence of thrombosis is higher among newborn infants than in any other stage of pediatric development. This fact is the consequence of labile characteristics of the neonatal hemostatic system, in addition to exposure to multiple risk factors and the wide use of vascular catheters. Venous thromboses, which mainly affect the limbs, the right atrium and renal veins, are more frequently seen...

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Inflammatory Cytokines and type 2 diabetes

Inflammatory cytokines increase in patients with type 2 diabetes (T2D) and metabolic syndrome. This review focuses on inflammatory cytokines such as C-reactive protein (CRP), tumor necrosis factor (TNF-α), and adiponectin, a cytokine produced by adipose tissue and associated with insulin sensitivity. Despite the major role of cytokines in the development of T2D, in the case of adiponectin still...

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Cardiac Hypertrophy in Newborn Infants *

The subject of cardiac hypertrophy unassociated with congenital malformation of the heart or great vessels in newborn infants has received scant attention. Although many text-books on pediatrics have been consulted, only one reference to the condition was found and that was by Von Reuss."1 He described a single case briefly and stated that the etiology was unknown. Recent studies indicate, howe...

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ژورنال

عنوان ژورنال: Mediators of Inflammation

سال: 1998

ISSN: 0962-9351,1466-1861

DOI: 10.1080/09629359890811